DNA deletion sparks separate outcomes of autism, schizophrenia
In children with a deletion on chromosome 22, having autism does not boost the risk of developing schizophrenia later in life, according to a new study.
The children in the study have 22q11.2 deletion syndrome, which is linked to a 25-fold increase in the risk of developing a psychotic condition such as schizophrenia. A deletion in the region is also associated with an increased risk of autism.
Some researchers have suggested that the relatively high autism prevalence in this population is the result of misdiagnoses of early signs of schizophrenia.
The new findings, published 21 January in Schizophrenia Research, support an alternate theory: Autism and schizophrenia are independent outcomes of the same genetic syndrome.
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- 16th March 2017