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Autism, schizophrenia, bipolar disorder share molecular traits, study finds

Most medical disorders have well-defined physical characteristics seen in tissues, organs and bodily fluids. Psychiatric disorders, in contrast, are not defined by such pathology, but rather by behavior.

A UCLA-led study, appearing Feb. 9 in Science, has found that autism, schizophrenia and bipolar disorder share some physical characteristics at the molecular level, specifically, patterns of gene expression in the brain. Researchers also pinpointed important differences in these disorders' gene expression.

"These findings provide a molecular, pathological signature of these disorders, which is a large step forward," said senior author Daniel Geschwind, a distinguished professor of neurology, psychiatry and human genetics and director of the UCLA Center for Autism Research and Treatment. "The major challenge now is to understand how these changes arose."


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https://www.sciencedaily.com/releases/2018/02/180208141346.htm
Date
8th February 2018
Source
Science Daily